Immunohistochemistry Kits and Reagents
Revvity Health Sciences Inc AlphaLISA Human Albumin Biotin Free Detection Kit, 5,000 Assay Points
AlphaLISA Human Albumin Biotin Free Detection Kit, 5,000 Assay Points
ABclonal Technology Myeloperoxidase (MPO) Rabbit pAb
Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils.
Electron Microscopy Sciences Aurion BSA Gold Tracer, EM-grade 25 nm 10 ML
Aurion Gold Tracers are used to visualize charged moieties in specimens: anionic tracers bind to polycationic moieties (basic proteins e.g. histones, cationic tracers bind to polyanionic moieties (membranes, acidic proteins). "Neutral" BSA coated gold tracers are useful for detecting open connections and tissue damage. Under proper conditions and with suitable microscopical techniques the tracers can also be used to follow cellular events in time.
Anionic Gold Tracers are prepared with BSA-c as particle conjugated protein. AURION Gold Tracers are shipped containing NaN3 as preservative. If they are intended for use in living organisms, the preservative has to be removed prior to use.
Particle size: EM-grade 25 nm
Enzo Life Sciences FLUOR DE LYS SIRT2 fluorometric drug discovery assay kit (1x96wells)
A FLUOR DE LYS fluorescent assay system. The SIRT2 Fluorescent Activity Assay/Drug Discovery Kit is a complete assay system designed to measure the lysyl deacetylase activity of the recombinant human SIRT2 included in the kit. The kit is ideal for chemical library screening for candidate inhibitors or activators or kinetic assay of the enzyme under varying conditions. The FLUOR DE LYS SIRT2 assay is based on the FLUOR DE LYSSubstrate and FLUOR DE LYS Developer combination. The assay procedure has two steps. First, the FLUOR DE LYS SIRT2 Substrate, which comprises a unique peptide based on amino acids 317-320 of p53 (Gln-Pro-Lys-Lys(Ac)), is incubated with SIRT2. Deacetylation of the substrate sensitizes the substrate so that, in the second step, treatment with the FLUOR DE LYSDeveloper II produces a fluorophore. Alternative name: Sirtuin 2 fluorescent assay kit. Applications: Fluorescent detection, HTS Cell-based assays, Activity assay.
Revvity Health Sciences Inc AlphaLISA Porcine IL-18 Detection Kit, 5,000 Assay Points
AlphaLISA Porcine IL-18 Detection Kit, 5,000 Assay Points
Electron Microscopy Sciences Pro-Craft 1/10 Hp Flex Shaft Motor, 220 V
Motor only comes with Shaft and Sheath.
Bioassay Systems EnzyChrom™ Choline Assay Kit. For quantitative determination of choline and evaluation of drug effects on choline metabolism.
For quantitative determination of choline and evaluation of drug effects on choline metabolism. Key Features: Use 20 µL samples. Linear detection range: colorimetric assay 1 to 100 µM, fluorimetric assay 0.2 to 10 µM choline. Method: OD570nm, or FL530/585nm. Samples: Serum, plasma, urine, saliva, milk, tissue, cells etc. Species: All. Procedure: Assay takes 30 min. Kit size: 100 tests. Detection limit: OD, FL: 1, 0.2 µM.
ABclonal Technology RANKL Rabbit pAb
This gene encodes a member of the TNF cytokine family, acting as a ligand for osteoprotegerin and playing a key role in osteoclast differentiation and activation. It also functions as a dendritic cell survival factor and regulates T cell-dependent immune responses. T cell activation induces expression of this gene, promoting osteoclastogenesis and bone loss. The protein activates the antiapoptotic kinase AKT/PKB via a signaling complex with SRC kinase and TRAF6, suggesting a role in apoptosis regulation. Disruption of the related gene in mice causes severe osteopetrosis, lack of osteoclasts, and defects in T and B lymphocyte differentiation, as well as failure to form lobulo-alveolar mammary structures during pregnancy. Two alternatively spliced transcript variants have been identified.
BioVendor, LLC Albumin Rat ELISA (96 wells)
Albumin Rat ELISA (96 wells). Immunoassay kit for quantitative measurement of rat albumin in serum, plasma, urine, or cell culture supernatant. SAMPLE REQ.: 5 l/well. CAL. RANGE: 501000 ng/ml. DETECTION LIMIT: 2.5 ng/ml. SUMMARY: Albumin is mostly a simple hydrophilic protein present in cells and body fluids. Albumin is synthesized in the liver, and serum albumin (69 kDa, pI 4.9) occupies 56-60% of total serum proteins. In normal human subjects, excretion of albumin into urine is low, about 30mg/day, but is increased in renal damage/disease. Shibayagis Albumin ELISA Kits can measure urinary albumin with high sensitivity, and are also applied to in vitro albumin biosynthesis system, checking of contamination with albumin in biological active substance preparations obtained by culture system, and liver transplantation experiments using NAR. Manufactured by FUJIFILM Wako Shibayagi Corporation, Japan.
Biotium CD13(WM15), CF594 conjugate, 0.1mg/mL
Recognizes an integral membrane glycoprotein of 150 kDa, identified as CD13 (also known as aminopeptidase-N). The antibody recognizes an extracellular epitope. The CD13 antigen is present on most cells of myeloid origin including granulocytes, monocytes, mast cells, and GM-progenitor cells. It is also expressed by the majority of AML, CML in myeloid blast crisis, and in a smaller fraction of lymphoid leukemias. CD13 is absent from normal lymphocytes, platelets and erythrocytes. CD13 is also present on fibroblasts; endothelial cells, epithelial cells from renal proximal tubules and intestinal brush border, bone marrow stromal cells, osteoclasts, and cells lining bile duct canaliculi. CD13 is identical to aminopeptidase N (APN), a prominent membrane-bound metalloprotease present on the surface of intestinal brush border and renal tubules. CD13 plays a role in metabolism of biologically active peptides, in phagocytosis, and in bactericidal/tumoricidal activities. It also serves
Abcam TripleStain IHC Kit: M&R&Rt on rodent tissue (DAB, DAB/Ni & AP/Red), 6ML
The TripleStain IHC Kit (ab183298) is designed to be used with user-supplied mouse, rat and rabbit primary antibodies to detect three distinct antigens on mouse tissue and cell samples or human tissue.
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical p38 MAPK InhIbItr VIII 1mg
An inhibitor of p38α (IC50 = 39 nM) and p38β MAP kinases with 82 and 93% inhibition, respectively, in a kinase assay (1 µM); selective for p38α and 38β, lacking activity at p38γ, p38δ, ERK1/2, and JNK1 at 1 µM; inhibits IL-1β, TNF-α, IL-6, IL-8, and IL-10, but not IFN-γ release from human peripheral blood mononuclear cells (IC50s = 30, 5, 17, 4, 10, and >1,000 nM, respectively); decreases EAr swelling in mouse models of allergic and chronic irritative contact dermatitis (0.5 mg/ear, topical)